Plesk web Hosting Panel Issues and Tutorials Web Hosting Issues Change default Outbound IP address for MailEnable? Windows and Plesk Server February 8, 2021December 9, 2022 admin #change mailenable IP, #MailEnable, #Plesk Connect to the server via RDP. Open Mailenable Administrator by finding MailEnable in the Programs section of the start menu (or Start screen on Windows 2012). Go to MailEnable Management > Servers > localhost > Services and Connectors . Right-click SMTP and choose Properties. Switch to Outbound tab and select desired outbound IP address: By default, the first adapter/interface added to the computer is always used for outbound traffic. Right-click on SMTP > Stop and then SMTP > Start.